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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCH2
All Species:
8.18
Human Site:
S1168
Identified Species:
18
UniProt:
O75038
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75038
NP_055453.2
1416
154668
S1168
P
S
L
G
L
G
R
S
R
E
N
L
A
G
A
Chimpanzee
Pan troglodytes
XP_001149239
1685
188441
N1211
T
V
V
S
H
L
H
N
T
S
V
M
S
G
H
Rhesus Macaque
Macaca mulatta
XP_001085424
1423
155915
S1175
P
S
L
G
L
G
R
S
R
E
S
L
L
G
A
Dog
Lupus familis
XP_546733
1387
151432
V1153
P
G
L
G
L
G
L
V
L
G
R
E
G
V
S
Cat
Felis silvestris
Mouse
Mus musculus
A2AP18
1501
164279
S1253
P
S
L
G
L
C
R
S
R
E
S
I
P
G
V
Rat
Rattus norvegicus
Q62688
1096
122754
Y873
M
G
K
K
V
R
E
Y
T
M
L
R
N
I
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q2VRL0
637
72514
K414
I
G
E
L
K
A
Q
K
F
V
K
H
A
A
N
Frog
Xenopus laevis
Q32NH8
758
87399
H535
P
G
N
D
F
V
R
H
N
A
W
Q
L
M
R
Zebra Danio
Brachydanio rerio
A5D6R3
784
89362
R561
N
N
S
R
Q
L
S
R
I
Y
P
S
A
Q
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25455
1318
146373
G1095
E
S
A
A
A
D
A
G
E
D
L
A
G
G
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783611
2724
302530
N1512
N
N
S
Y
L
R
K
N
E
D
H
Y
N
L
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
46.4
94
78.7
N.A.
77.2
21.2
N.A.
N.A.
21.2
24.7
24.5
N.A.
24.2
N.A.
N.A.
26.4
Protein Similarity:
100
59.9
95.4
82.9
N.A.
81.6
36.7
N.A.
N.A.
30.7
35.3
35
N.A.
40.3
N.A.
N.A.
35.7
P-Site Identity:
100
6.6
86.6
33.3
N.A.
66.6
0
N.A.
N.A.
6.6
13.3
6.6
N.A.
13.3
N.A.
N.A.
6.6
P-Site Similarity:
100
33.3
93.3
40
N.A.
80
6.6
N.A.
N.A.
13.3
13.3
13.3
N.A.
26.6
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
10
10
10
10
0
0
10
0
10
28
10
19
% A
% Cys:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
10
0
0
0
19
0
0
0
0
0
% D
% Glu:
10
0
10
0
0
0
10
0
19
28
0
10
0
0
0
% E
% Phe:
0
0
0
0
10
0
0
0
10
0
0
0
0
0
0
% F
% Gly:
0
37
0
37
0
28
0
10
0
10
0
0
19
46
10
% G
% His:
0
0
0
0
10
0
10
10
0
0
10
10
0
0
10
% H
% Ile:
10
0
0
0
0
0
0
0
10
0
0
10
0
10
0
% I
% Lys:
0
0
10
10
10
0
10
10
0
0
10
0
0
0
0
% K
% Leu:
0
0
37
10
46
19
10
0
10
0
19
19
19
10
0
% L
% Met:
10
0
0
0
0
0
0
0
0
10
0
10
0
10
0
% M
% Asn:
19
19
10
0
0
0
0
19
10
0
10
0
19
0
10
% N
% Pro:
46
0
0
0
0
0
0
0
0
0
10
0
10
0
0
% P
% Gln:
0
0
0
0
10
0
10
0
0
0
0
10
0
10
0
% Q
% Arg:
0
0
0
10
0
19
37
10
28
0
10
10
0
0
19
% R
% Ser:
0
37
19
10
0
0
10
28
0
10
19
10
10
0
28
% S
% Thr:
10
0
0
0
0
0
0
0
19
0
0
0
0
0
0
% T
% Val:
0
10
10
0
10
10
0
10
0
10
10
0
0
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
10
0
10
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _